Ultrastructural Localization of Toxocara canis Larval Antigen Reacted with a Seropositive Human Serum
نویسندگان
چکیده
منابع مشابه
Ultrastructural localization of Toxocara canis larval antigen reacted with a seropositive human serum.
Excretory-secretory products of Toxocara canis larvae have been considered as a major functional antigen in immune responses against toxocariasis. We studied ultrastructural localization of T. canis second-stage larval antigen using a seropositive human serum under immunogold electron microscopy. High-density gold particles were observed in the secretory cells, excretory duct, intestinal epithe...
متن کاملMethod for detecting circulating Toxocara canis antigen and its application in human serum samples.
Diagnosis of larval migrans (LM) is usually done by immunodiagnostic methods. These methods, however, simply show the presence or absence of antibody but not the active infection of the patients. Therefore, we aimed to establish a diagnostic method for detecting circulating Toxocara canis antigen using a sandwich, ELISA. Monoclonal antibodies (MAb) were produced against the excretory-secretory ...
متن کاملResponse of human leukocytes after stimulation with excreted-secreted toxocara canis larval antigens
Background Specific immunotherapy by administration of allergen extracts has been successfully used in asthma, allergic rhinitis and for venom. The identification of molecules which could be used as adjuvants in anti-allergy immunotherapeutic preparations is highly desirable. Antiallergy immunotherapy has been associated with the induction of regulatory T cells. Helminths possibly downmodulate ...
متن کاملToxocara canis and Toxocara catis
mopolitan roundworms that infect dogs, especially puppies, and cats. T. canis infection in humans occurs by ingestion of the embryonic eggs, which are shed in the feces of infected dogs. Toxocariasis is manifested in three different syndromes: visceral larva migrans (VLM), ocular larva migrans (OLM), and covert toxocariasis (1, 2). VLM is usually a disease of children 1 to 6 year old, and it ma...
متن کاملAn improved method to obtain antigen-excreting Toxocara canis larvae.
Toxocara canis is a dog helminth which causes visceral larva migrans (VLM) when infecting humans as a larva. The infection is demonstrated by detecting IgG antibodies against excretory-secretory larval antigens (ESLA) in serum by ELISA. The production of ESLA involves the collection of adult worms from dog puppy stools, the separation of eggs from dissected uteri, and the in vitro growing of eg...
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ژورنال
عنوان ژورنال: The Korean Journal of Parasitology
سال: 2009
ISSN: 0023-4001
DOI: 10.3347/kjp.2009.47.1.65